When you have cold sores, you’ll develop fluid-filled blisters beneath the skin’s surface. It is the blister that contains the contagious herpes virus.

It is true that FDA-approved creams and the latest medical devices can heal cold sores faster. But, there is no getting around the fact that blistering is a part of the lifecycle of a cold sore. You haven’t treated the cause but symptoms, so there is no medical reason why blistering won’t have taken place.

Because blisters must occur, if you encounter some lip pain without a sore, you need a diagnosis by a doctor. There is a possibility that an alternative medical problem has led to the condition. It could be something more serious than a fever blister.

We’ll help you to understand the cold sore lifecycle. You’ll also learn about skin conditions mistaken for fever blisters. Keep reading to find out why you may be experiencing lip or mouth pain.

What Does a Cold Sore Look Like?

Although cold sore blisters are unique, they all have common traits.

Typically forming in clusters, cold sores are firm to the touch and filled with fluid.[1] The blisters can often be described as “tight” due to the fluid compression within the blister itself. This can lead to pain in the problem area.

Often reddish or brownish tan in color, they can produce a harsh visual. This is particularly important when the outbreak is aggressive. Due to intense swelling, some blisters can pass for altercation marks in some cases.

Until the blister bursts and slowly begin to scab, it is typical for a “fat lip” appearance to take hold. You’ll notice redness and swelling. This is one reason why cold sores are not only painful but also embarrassing.

To summarize:

  • Cold sores usually have the appearance of raised blisters. These sores typically form in clusters although one blister having a more prominent appearance is not uncommon.
  • Cold sores can be painful during your initial outbreak. If you have had any form of lip inflammation in the past, odds are this will be much more intense. This alone will likely let you know that something is serious. As the blister and surrounding areas begin to swell, more pressure is created. Once the sore bursts and is considered “open” the pain can be quite intense. This is known as the ulcer stage.
  • Notice the colors. Cold sore blisters are reddish or a light tan in color. As they progress, they often feature a yellowish tint. This usually sets them apart from other types of lip and mouth complications.

Cold Sore Lifecycle

Although it is possible to heal a cold sore in days, the cycle is still the cycle. Unlike many skin conditions and general illnesses, an outbreak must pass through a series of stages.

Listed below are the lifecycle stages of a cold sore and the symptoms you can expect:

  • Often regarded as the tingle stage, the prodromal stage of a cold sore cycle deals with sensation only. The first sign of trouble regularly features a tingle or burning sensation in a distinct area of the lip. The exact area is often where HSV-1 transmission occurred.
  • The second stage of the process is known as the blister stage. During this timeframe, small blisters, typically in clusters, will begin to form where the tingle first occurred. Starting to increase in size, the blisters will swell and develop fluid. Additionally, the skin surrounding the problem area will also swell.
  • Regarded as the most painful stage, the ulcer portion of the lifecycle can be the most difficult. During this stage, the blisters begin to burst, and ulcers develop. Regarded as an open sore at this stage, the risk of infection, as well as transmission to others, is at its peak.
  • Not long after the ulcer forms, a yellowish/brown crust begins to cover the area. This is known as the scab stage. Although scabbing can produce painful cracks and even bleeding, burning, and itching, this is a sign of positive healing. Patience is critical at this stage. Forcibly peeling the scab can result in some rather serious consequences that can lead to infection.
  • As the scab starts to flake away naturally, the new skin is revealed. Although quite tender and reddish/pink in color, this portion of the cycle is known as the healing stage. Once you have arrived at this point, your outbreak has ended, and you are no longer contagious.

Although the cold sore cycle is quite detailed, the entire process (through natural means) usually only lasts 8-14 days. The cycle can be cut in half and then some with effective OTC medication, such as HERP-B-GONE.

It should also be noted that cold sores are deemed contagious from the initial symptom until fully healed.

Do Cold Sores Always Have a Blister Stage?

The odds of healing a cold sore outbreak and stopping blister formation at the tingle stage are very slim. Although treatment at the earliest of symptoms is encouraged, no medication applied, even at the tingle stage, can prevent a blister.

If you have encountered lip irritation without a visual representation, it could be related to something else.[2] This is especially true if the sensation concluded without producing a blister, bump, rash, etc.

To recap:

  • The activation of HSV-1 produces cold sores. While these blisters can be treated and healed in a reasonably short time, the blisters must form.
  • If you have experienced some form of odd lip sensation but nothing more, chances are that it isn’t cold sores. Various foods, drinks, and changes in the environment can lead to unusual sensations on and around your lips.

Skin Conditions that Are Mistaken for Cold Sores 

The lips are a sensitive region of the body. For this very reason, it does not take much to produce some level of irritation. While that irritation does not always take the form of a blister, some elements can create issues.

It is also not uncommon for these issues to be mistaken for cold sores. If you have never had a legitimate cold sore outbreak in the past, any blister could be mistaken for a fever blister.

My cold sores aren't blistering

Detailed below are just a few of the most common skin conditions and irritations that could be mistaken for cold sores:

  • One ailment that is often confused with cold sores is canker sores. Typically found on the inside of the mouth, canker sores produce what essentially amounts to small knots. These painful blisters and nodules can make chewing (and speaking) more difficult. Canker sores are caused by irritation and not a virus.[3] Just the simple act of biting your cheek with your teeth can lead to a canker sore.
  • Shaving can lead to complications around the lips and mouth. Minor cuts and scrapes can produce blisters. Additionally, ingrown hairs can lead to painful sores. When these sores develop on the fringe of the lip, they can easily be mistaken for cold sores. Typically healing on their own, ingrown hairs are not a major issue but they are certainly painful and visually annoying.
  • Various allergic reactions can produce bumps around the mouth and lips. Certain foods, drinks, lipsticks, lip balms, etc., can be to blame. This is especially true if you have known allergies.
  • It is also possible that what you fear is a cold sore could be an insect bite. If you enjoy exploring the great outdoors, it is indeed possible that a bee or mosquito could have caused your painful bump or blister.

Why You Need a Diagnosis from a Doctor 

Receiving a proper diagnosis from your doctor is critical because making blind assumptions and conclusions is never wise. Furthermore, attempting to treat the unknown with the wrong type of medication could make matters worse.

If you have had cold sores in the past, you likely know how to spot the next one. The issue is usually recognized, treated, and then healed in a timely fashion. However, just because an unknown blister has appeared on your lip does not mean it is a cold sore.

To summarize:

  • If you are working with the conclusion that you have a cold sore without a blister, treating it as a cold sore is unwise. Attempting to treat the unknown with the assumed correct treatment can be worse than taking no action at all.

Conclusion

Because it has been established that cold sores must follow a natural cycle, healing an outbreak before a sore developing is unlikely. It is critical to know what is causing your issue. If your lip pain, tingle, burning, etc. is not a cold sore, you need to seek medical attention.

The final takeaway is two-fold. The first point of importance is understanding the complexity of a cold sore and its symptoms. The more you know about HSV-1 and fever blisters the more you will know about your situation.

Secondly, since cold sores are not able to be healed before the blister stage, what is the real concern? Do you have an allergy? Do you have an insect bite? Consulting with your physician can eliminate the natural inclination to self-diagnose and treat it with the wrong medication.

Although cold sores can be painful and annoying, they do not have to be a confusing issue. Trying to treat any medical condition based on assumption can be dangerous. The more you understand about HSV-1, the better you will be if an outbreak does occur.

References

  1. https://www.webmd.com/skin-problems-and-treatments/ss/slideshow-cold-sores
  2. https://www.magonlinelibrary.com/doi/10.12968/denu.2015.42.6.588
  3. Chavan, M. , Jain, H. , Diwan, N. , Khedkar, S. , Shete, A. and Durkar, S. Recurrent aphthous stomatitis: a review. Journal of Oral Pathology & Medicine, 2012;41: 577-583. doi:10.1111/j.1600-0714.2012.01134.x